Biotin and derivatives
Medchemexpress LLC Biotin-labeled ODN 2395 sodium | 1254617-22-5 | 1 MG
Biotin-labeled ODN 2395 sodium is a C class oligodeoxynucleotide and a TLR9 agonist. It is used for research purposes to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
- Is a C class oligodeoxynucleotide
- Acts as a TLR9 agonist
- Facilitates evaluation of CpG ODN cellular uptake and localization
- Designed for use with biotin detection systems and light microscopy
Medchemexpress LLC Biotin-PEG-thiol (MW 2000) | 98.0% | 2000 (Average) | 100 MG
Biotin-PEG-Thiol (MW 2000) is an active compound. It is pegylated by binding to streptavidin or antibiotin with high affinity and specificity, allowing it to modify biomolecules, proteins, peptides, and other small molecule materials. This compound is widely used in the research of agent release and nano new materials.
- Purity: 98.0%
- Molecular weight: 2000 (Average)
- Target: Fluorescent dye
- Pathway: Others
- In vitro solubility: DMSO: 125 mg/mL (Need ultrasonic)
- Storage conditions: -20°C, protect from light, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen).
Medchemexpress LLC Biotin-Gastrin Releasing Peptide, human TFA | 3085.67 (free base) | 1 MG
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties. This product is for research use only.
- Biotinylated gastrin releasing peptide (GRP)
- Functions as a neuropeptide with growth-stimulatory properties
- Functions as a neuropeptide with tumorigenic properties
- For research use only
Medchemexpress LLC 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | 2183440-73-3 | ≥98.0% | C16H26N2O8 | 250 MG
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker designed for use in the synthesis of PROTACs. These compounds exploit the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins, offering a novel approach for targeted therapy.
- Utilized in the synthesis of PROTACs
- Leverages the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Alkyl/ether-based linker
Medchemexpress LLC Bz-(Me)Tz-NHS | 1454558-58-7 | MFCD00076258 | C₁₉H₂₀N₅O₅S | 25 MG
Bz-(Me)Tz-NHS is a click chemistry reagent that contains a methyltetrazine group. It functions as a 3rd generation Click-Linker for Cu-free click conjugation, primarily used in antibody-drug conjugate (ADC) related research.
- Contains a methyltetrazine group
- Functions as a 3rd generation Click-Linker
- Designed for Cu-free click conjugation
- Used in antibody-drug conjugate (ADC) related research
Medchemexpress LLC Sulfo-TAG NHS ester disodium | 482618-42-8 | C43H39N7Na2O16RuS4 | 5 MG
Sulfo-TAG NHS ester disodium is an N-hydroxysuccinimide ester that can be coupled to proteins via primary amine groups. It can be used for antibody labeling.
- Couples to proteins via primary amine groups
- Used for antibody labeling
- Compatible with lyophilized and solution antibodies
- Can be used with protein quantification methods
- Antibody labeling performed at room temperature in the dark
- Labeling ratio can be determined spectrophotometrically
Medchemexpress LLC Biotin-α-Hypophamine | 99.3% | 1233.48 | 5 MG
Biotin-Oxytocin is a biologically active peptide, also known as Biotin-α-Hypophamine or Biotin-Oxytocic hormone. It is an oxytocin derivative N-terminally labeled with biotin.
- Biologically active peptide
- N-terminally labeled with biotin
- Targets oxytocin receptor
- Involved in GPCR/G protein pathway
Medchemexpress LLC Mal-PEG3-C1-NHS ester | 2230016-26-7 | 95.0% | 384.34 g/mol | C16H20N2O9 | 50 MG
Mal-PEG3-C1-NHS ester is a non-cleavable 3-unit polyethylene glycol (PEG) linker bearing a maleimide and an N-hydroxysuccinimide (NHS) ester. It is supplied for research use to facilitate conjugation between amine and thiol groups during antibody-drug conjugate (ADC) synthesis, and is provided as a solution for low-temperature storage.
- Non-cleavable 3-unit polyethylene glycol linker.
- Terminal maleimide and NHS ester functional groups for thiol and amine coupling.
- Suitable for antibody-drug conjugate (ADC) synthesis.
- Purity approximately 95.0%.
- Supplied as a solution; store at -20°C for up to 2 years.
Sigma Aldrich Fine Chemicals Biosciences Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 100MG
Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 100MG
Medchemexpress LLC Biotin-C5-azide (decarboxybiotin-n3) | 1260586-88-6 | C10H17N5OS | 5 MG
Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent utilized for preparing biotinylated conjugates. It operates as a click chemistry reagent, incorporating an azide group. This group enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Biotin reagent
- Can be used to prepare biotinylated conjugates
- Click chemistry reagent
- Contains an azide group for CuAAc and SPAAC reactions
Medchemexpress LLC N3-C2-NHS ester | 850180-76-6 | MFCD24452814 | 99.8% | 212.16 g/mol | C7H8N4O4 | 10 MG
N3-C2-NHS ester is a noncleavable ADC linker and NHS-activated ester reagent used for bioconjugation and the synthesis of antibody-drug conjugates. It is an oil-like, colorless to off-white small molecule with high purity and good solubility in DMSO for research applications.
- Noncleavable ADC linker for antibody-drug conjugation.
- NHS-activated ester enables amine-selective bioconjugation.
- High purity suitable for synthetic chemistry (≈99.8%).
- Soluble in DMSO; ultrasonic assistance may be required.
- Store at -20 °C in pure form; follow solvent-storage guidelines.
- Available in small research sizes, including 10 MG.
Medchemexpress LLC Biotin-PEG3-acid 250mg | 252881-76-8 | 447.55 g·mol⁻¹ | C19H33N3O7S | 250 MG
Biotin-PEG3-acid is a biotin-labeled PEG3 linker with a terminal carboxylic acid, supplied as a solid for use in conjugation and PROTAC linker synthesis. It provides a hydrophilic spacer arm to attach biotin to small molecules or probes, enabling affinity capture, purification, and detection workflows.
- Biotin-labeled PEG3 linker with carboxylic acid terminus.
- Suitable for coupling chemistries such as amide bond formation.
- Used in PROTAC synthesis, biotinylation, pull-downs, and detection assays.
- Molecular weight 447.55 g·mol⁻¹ and CAS 252881-76-8.
- Purity 98.0%.
- Supplied as a 250 MG solid; other sizes available.
Medchemexpress LLC Biotinamidocaproyl hydrazide | 109276-34-8 | MFCD00077659 | 99.8% | 371.50 g/mol | C16H29N5O3S | 10 MG
Biotin LC hydrazide is a long-chain biotinylation reagent used to derivatize periodate-oxidized carbohydrates on glycoproteins and other biomolecules. The hydrazide moiety reacts with aldehydes generated by mild oxidation to form stable hydrazone linkages, while the long-chain spacer arm improves accessibility for detection and affinity capture. Intended for research use only.
- Reacts with periodate-oxidized carbohydrates and glycoproteins.
- Introduces a biotin tag via hydrazide chemistry for avidin/streptavidin detection.
- Long-chain spacer reduces steric hindrance and improves binding accessibility.
- Suitable for labeling, detection, and affinity purification workflows.
- Provided as a stable white solid for easy handling and storage.
Medchemexpress LLC DBCO-NHS ester 2 500mg | 1384870-47-6 | 430.45 | C25H22N2O5 | 500 MG
DBCO-NHS ester 2 is a dibenzylcyclooctyne (DBCO)-derived N-hydroxysuccinimide (NHS) ester used as an amine-reactive linker for bioconjugation and antibody-drug conjugate synthesis. The reagent enables copper-free click chemistry via strain-promoted alkyne-azide cycloaddition (SPAAC) and is supplied as a powder for laboratory use.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free click chemistry.
- Amine-reactive NHS ester for efficient labeling of proteins, peptides, and small molecules.
- Appropriate for antibody-drug conjugate (ADC) linker synthesis and general bioconjugation.
- High reported purity in product documentation.
- Powder form with long-term storage at -20°C; soluble in DMSO (≈14.29 mg/mL) with ultrasonic assistance.
Medchemexpress LLC DBCO-NHS ester 3 100mg | 1393350-27-0 | 416.43 | C24H20N2O5 | 100 MG
DBCO-NHS ester 3 is an amine-reactive dibenzocyclooctyne (DBCO)-based N-hydroxysuccinimide (NHS) ester used as a clickable linker for constructing antibody-drug conjugates and for labeling amine-containing biomolecules via strain-promoted alkyne-azide cycloaddition. Supplied as a 100 MG solid for research use.
- Amine-reactive NHS ester enables covalent coupling to primary amines.
- DBCO moiety supports copper-free click chemistry (SPAAC) with azides.
- Suitable for antibody-drug conjugate linker synthesis and protein labeling.
- Provided in small research-scale solid quantities for laboratory workflows.
- Molecular formula C24H20N2O5; molecular weight 416.43 g/mol.